Myopathies typically present with proximal or generalised muscle weakness, but it is important for clinicians to recognise they may also have other distributions. The case includes several learning points:
examination myopathy patient Adult onset
She specifically denies any symptoms of diplopia and states that her symptoms do not fluctuate during the day or when she becomes fatigued. Causes of CK elevation other than neuromuscular disease include: Patients with periodic paralysis or metabolic myopathies can have recurrent attacks of weakness over many years, while a patient with acute rhabdomyolysis due to cocaine may have a single episode. Oral and intravenous steroids are most commonly used, with favorable results in most cases. This pattern of weakness predominantly involves the distal muscles of the upper or lower extremities anterior or posterior compartment muscle groups Box 14 Dimachkie and Barohn.
This should be suspected if the urine tests positive for blood but no red blood cells are identified. Toxic Myopathy Medications Steroids Cholesterol-lowering medications: The exact mechanism by which statins cause myopathy is unknown, but mitochondrial dysfunction and decreased coenyzme Q10 levels have been postulated.